Well, I've managed to get MythTV working fine with Fedora Core 5. XMAME isn't quite working in conjunction with it, because of a feature of the last version of Metacity window manager that caused the fullscreen window to not have keyboard focus. I think this is reverted in version 2.14.3 which I'm downloading right now.
Haven't yet got an iTunes server running on the box. I've read about the Multi-Threaded DAAP Daemon which seems to be a better DAAP server than the one I recommended previously. I'll update my little tutorial if I start using that instead.
Fedora Core 5 seems to be pretty good. Not 100% sure about the new bubbly look, but if it continues to offend my sensibilities I really should try and create my own desktop skin. Mind you most of the time it sits quietly behind MythTV, so It's not such a big deal.
